>For your viewing convenience, the 2017 In Vitro Biology Meeting Final Program has been broken down by day.
Daily Program-at-a-Glance
| Time | Event | Location |
|---|---|---|
| 7:00 am – 5:00 pm | Registration | Ballroom C Lobby |
| 10:00 am – 3:30 pm | Exhibits and Posters | Ballroom C |
| Morning | 7:00 am – 12:30 pm | |
| 7:00 am – 8:00 am | In Vitro – Animal Editorial Board Meeting | University AB |
| Student Affairs Breakfast | Room 304 | |
| 8:00 am – 10:00 am | Scaffolds from Plants and Synthetic Materials for Human Tissue Engineering | Room 306BC |
| 10:00 am – 10:30 am | Coffee Break | Ballroom C |
| Education Committee Meeting | Governors Board Room | |
| 10:30 am | Closing of City of Oaks Silent Auction | Ballroom C |
| 10:30 am – 12:30 pm | Practical Media Improvement Using DOE: Case Study Comparisons of a Commercially Available MS Media Improvement Kit | Room 306BC |
| Medicinal Plants | Room 305 | |
| Microfluidics for Applied Biology | Room 306A | |
| Afternoon | 12:30 pm – 6:00 pm | |
| 12:30 | Announcement of the City of Oaks Silent Auction Winners | Ballroom C Foyer |
| 12:30 pm – 1:30 pm | 2018 Program Planning Committee Meeting | University AB |
| 1:30 pm – 2:30 pm | Interactive Poster Sessions Germplasm Preservation and Others In Vitro Animal Cell Sciences Interactive Poster Session Metabolic Engineering & Others |
Ballroom C |
| 2:30 pm – 3:30 pm | Odd Poster Authors will be present | Ballroom C |
| 3:30 pm – 5:00 pm | Posters to be removed from Exhibit Hall | |
| Exosomes/Secretomes | Room 306A | |
| Start Up for Commercialization, Idea Development, and IP Capture | Room 306BC | |
| Secondary Metabolites | Room 305 | |
| 5:00 pm – 5:30 pm | SIVB Business Meeting (All Members Are Urged to Attend) Student Award Presentations |
Room 306 BC |
| 5:45 pm – 9:00 pm | A Night at the Museum Admittance by Advance Ticket Holders Only |
Off Property |
Tuesday, June 13
| 7:00 am – 5:00 pm | Registration | Ballroom C Lobby |
SCAFFOLDS FROM PLANTS AND SYNTHETIC MATERIALS FOR HUMAN TISSUE ENGINEERING
Conveners: Joshua Z. Gasiorowski, Midwestern University, and Pamela J. Weathers, Worcester Polytechnic Institute
| 8:00 am – 10:00 am | Plenary Symposium | Room 306BC |
Advanced biomanufacturing is an important emerging discipline to generate new, biologically-relevant materials and devices. The process of biomanufacturing relies on exploiting cell-derived building blocks, materials and synthesis systems – most commonly from a single organism (i.e. plant, animal, or bacterial cell). Consequently, the scope of biomanufacturing has been limited by the physical and intellectual isolation of basic research in different organisms and systems to their respective biological “kingdoms.” Current limitations in biomanufacturing can be overcome through the development of novel engineering tools, and also by exploiting contributions across living kingdoms to use naturally occurring materials and/or bioinspired architecture. In this session new approaches will described for generating the architectural scaffolds for eventual use in tissue and organ engineering.
| 8:00 |
Introduction (J. Z. Gasiorowski and P. J. Weathers) |
|
| 8:05 | PS-6 | Plantimals: Plant Tissues as Scaffolds for Human Tissue Engineering Glenn Gaudette, Worcester Polytechnic Institute |
| 9:00 | PS-7 | TBD Jennifer West, Duke University |
| 9:55 | Discussion |
| 10:00 am – 10:30 pm | Coffee Break | Ballroom C |
PRACTICAL MEDIA IMPROVEMENT USING DOE: CASE STUDY COMPARISONS OF A COMMERCIALLY AVAILABLE MS MEDIA IMPROVEMENT KIT
Conveners: Randall P. Niedz, USDA-ARS U.S. Horticultural Research Laboratory, and Michael E. Kane, University of Florida
| 10:30 am – 12:30 pm | Plant Symposium | Room 306BC |
Media improvement is critical for improving the growth and regeneration of plant tissues in vitro. During the 2015 SIVB Meeting, a symposium was organized to discuss the benefits, challenges and the “nuts and bolts” of using a statistics-based approach, known as Design of Experiments (DOE) to improve plant tissue culture media. This approach provides researchers with a method to efficiently screen multiple media factors, simultaneously. However, systematic testing of the effects of the more than a dozen mineral salts included in most plant culture media, is sometimes perceived by laboratories as daunting and beyond their capabilities. To overcome this limitation PhytoTechnology Laboratories recently developed a DOE-based media kit, the Deconstructed MS Media Kit, to facilitate the use of DOE for media improvement. This session will review the DOE approach to media development, the DOE principles used by the MS Media Kit, and the kit’s utility. Research and commercial micropropagation laboratories will present case studies of the kit’s usage. A discussion will follow the presentations.
| 10:30 | Introduction (R. P. Niedz and M. E. Kane) | |
| 10:40 | P-23 | MS Media Kit and Design of Experiments (DOE) Overview Randall P. Niedz, USDA-ARS U.S. Horticultural Research Laboratory |
| 11:10 | P-24 | The PhytoTechnology Laboratories Deconstruction MS Media Kit David Hart, PhytoTechnology Laboratories |
| 11:30 | -25 | Case Study #2: Using the Deconstruction MS Media Kit to Evaluate Factors Influencing In Vitro Growth in Endangered Exceptional Species Valerie Pence, Cincinnati Zoo and Botanical Garden |
| 11:50 | P-26 | Screening Experiments for Mineral Nutrition Using De-constructed MS: Observing Subsequent Effects on Rooting and Acclimatization Jeffery Adelberg, Clemson University |
| 12:10 | Discussion |
MEDICINAL PLANTS
Conveners: Debora A. Esposito, North Carolina State University, and Nirmal Joshee, Fort Valley State University
| 10:30 am – 12:30 pm | Plant Symposium | Room 305 |
From Alaskan berries to chicory roots, there are hundreds of remarkably common herbs, flowers, berries and plants that serve all kinds of important medicinal and health purposes that might surprise you. Medicinal Plants 2017 session will showcase recent discoveries and developments in Natural Products drugs discovery and development.
| 10:30 | Session Overview (D. A. Esposito and N. Joshee) | |
| 10:35 | P-27 | Technological and Health Relevant Attributes of Spray Dried Blueberry Polyphenol-protein Aggregates Roberta Targino Pinto Correia, Universidade Federal do Rio Grande do Norte |
| 11:00 | P-28 | Dietary Long-chain PUFAs Enrich Porcine Alveolar Macrophages and Modulate Inflammatory Response Kathleen Walter, North Carolina State University |
| 11:25 | P-29 | Berry Extracts to Protect Skin from Inflammation Sierra Bonney, North Carolina State University |
| 11:50 | P-30 | Bitter Receptors Control Glucose Absorption in the Gut by Modifying the GPCR Signaling Cascade Kimberly M. Palatini-Jackson, North Carolina State University |
| 12:15 | Discussion |
MICROFLUIDICS FOR APPLIED BIOLOGY
Conveners: Jessica Monserrate, Bayer CropScience, Miguel Acosta, Arbiom, and Sara Lenzen, Bayer CropScience
| 10:30 am – 12:30 pm | Animal Symposium | Room 306A |
Microfluidics is a popular field in the life sciences and biotechnology because it can be customized for a wide range of application including: drug delivery, point of care devices and diagnostics as well affording researchers the ability to analyze single cell responses to soluble cues. This is but a small sliver of possibilities and the diversity of applications is only growing. In this session we touch on some of the microfluidic tools being developed for applied biology.
| 10:30 | Introduction (J. Monserrate and M. Acosta) | |
| 10:35 | A-11 | Development of a Tumor-on-a-Chip for Hypoxia Studies Glenn Walker, North Carolina State University |
| 11:00 | A-12 | Liquid Metals for Microfluidics Michael Dickey, North Carolina State University |
| 11:35 | A-13 | Programming Bacteria in Time and Space Lingchong You, Duke University |
| 12:10 | Discussion |
IN VITRO ANIMAL CELL SCIENCES INTERACTIVE POSTER SESSION
Moderator: Durga Attili, University of Michigan Medical School
| 1:30 pm – 2:30 pm | Animal Interactive Poster Session | Ballroom C |
| A-2000 | Protective Effects of Oat Bioactives on Biomarkers of Gastrointestinal Cell Injury Mikayla M. Bowen, University of North Carolina Chapel Hill, Ashley Buige, Weston Bussler, and Slavko Komarnytsky |
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| A-2001 | Absorption and Distribution of the Antimalarial Drug Artemisinin Delivered Orally as Dried Leaves of Artemisia annua Matthew Desrosiers, Worcester Polytechnic Institute, and P. J. Weathers |
|
| A-2003 | Identifying the Role of Phosphorylation on Interdomain Communication in Hsp70 Laura Knighton, University of North Carolina at Charlotte, and Andrew W. Truman |
|
| A-2004 | A Histological Comparison of Ear Skin Regeneration in Acomys and Mus. A. Sandoval, University of Florida, J. Brant, and M. Maden |
|
| A-2007 | Opportunities for Translating Large-scale Cell Culture Technologies to the Production of Sustainable Clean Meat Christie Lagally, The Good Food Institute, and Liz Specht |
GERMPLASM PRESERVATION AND OTHERS
Moderator: Hong Luo, Clemson University
| 1:30 pm – 2:30 pm | Plant Interactive Poster Session | Ballroom C |
| P-2003 | A Lab-to-Land Approach for Conservation of Shirui Lily (Lilium macklineae) – An Endangered Heritage Flower of Manipur, India. M. R. Sahoo, ICAR Research Complex for North Eastern Hill Region, M. P. Devi, M. Dasgupta, N. Prakash, and S. V. Ngachan |
|
| P-2004 | Plant Production Through Somatic Embryogenesis of Theobroma cacao L. Leaf Cultures Esther E. Uchendu, University of Ibadan, Omolola O. Oso, and Victor O. Adetimirin |
|
| P-2005 | Improving Resistance to Potato Common Scab by the Production of Somaclones Habituated to Thaxtomin A Safa Labidi, University of Sherbrooke, and Nathalie Beaudoin |
METABOLIC ENGINEERING AND OTHERS
Moderator: Margaret M. Young, Elizabeth City State University
| 1:30 pm – 2:30 pm | Plant Interactive Poster Session | Ballroom C |
| P-2010 | Red and White PAP1-controlled Arabidopsis Cells Are Dependent Upon TT8 Yue Zhu, North Carolina State University, and De-Yu Xie |
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| P-2011 | Suspension Culture of Programmed Red vs. Wild-type Cells of Tobacco Seyit Yuzuak, North Carolina State University, and De-Yu Xie |
|
| P-2012 | Generation of Chemically Induced Mutations Using Embryogenic Coffee Cell Suspensions and In Vitro Selection for Salt Tolerance Andrés M Gatica-Arias, Universidad de Costa Rica, Alejandro Bolivar-González, and Marta F Valdez-Melara |
Tuesday, June 13
Odd Poster Authors will be present
2:30 pm – 3:30 pm
EXOSOMES/SECRETOMES
Conveners: Michael J. Fay, Midwestern University, and Kolla Kristjansdottir, Midwestern University
| 3:30 pm – 5:00 pm | Animal Symposium | Room 306A |
This session will focus on two methods of intercellular communication, expression of intracellular proteins ectopically on the cell surface and secretion of exosomes that contain proteins, lipids, and RNAs. Hsp90 is an intracellular protein that has been extensively studied as a chemotherapeutic drug target. Recently it has been shown that a unique form of Hsp90 is ectopically expressed on the cell surface of cancer cells and may mediate migration from the primary tumor site. In this session, a tethered Hsp90 inhibitor will be introduced that recognizes only the extracellular form of Hsp90 and results in specific labeling of cancerous cells. Another method of intercellular communication involves secretion of exosomes that can contain proteins, lipids, and RNAs. The involvement of exosomes in intercellular communication has become a major focus of research, and investigators are trying to determine the role of exosomes in physiological and pathophysiological processes. In this session we will learn about the potential for exosomes to be used to transport chemotherapeutic drugs to cancer cells. We will also learn about the role of exosomes in ocular health and disease.
| 3:30 | Introduction (M. J. Fay and K. Kristjansdottir) | |
| 3:35 | A-15 | Fluor-Tethered Inhibitors of Hsp90 Reveal Secretion and Reinternalization of Hsp90 Is Associated with Metastatic Progression Timothy Haystead, Duke University School of Medicine |
| 4:00 | A-16 | Using Exosomes for Drug Delivery Elena Batrakova, University of North Carolina at Chapel Hill |
| 4:25 | A-17 | The Potential of Ocular Exosomal Biomarkers as Therapeutic Targets, and as Diagnostic and Prognostic Indicators Mikael Klingeborn, Duke University Medical Center |
| 4:50 | Discussion |
START UP FOR COMMERCIALIZATION, IDEA DEVELOPMENT, AND IP CAPTURE
Conveners: Allan R. Wenck, Bayer CropScience, and Hoang Nguyen, University of California, Davis
| 3:30 pm – 5:00 pm | Plant Symposium | Room 306BC |
The contributions of biological scientists to society have surpassed the boundary of academia. There are many successful biotechnology companies created or operated by biological scientists. The advancement of the internet-shared information, new biological technologies and especially start-up incubators has effectively nurtured many research ideas into biological businesses. Various case studies indicated that the process of turning ideas to fruitful companies may or may not be generalized by a linear pathway. Typically, a biological startup begins with (1) preliminary research and idea development, or opportunity recognition, (2) intellectual property rights protection, (3) fund raising by obtaining venture capital, (4) team building toward technology and product development, (5) product marketing and profit making. At the Research Triangle Park (RTP) in North Carolina, a startup hub has been created to support agricultural scientists and businesses. Biological scientists and inventors, from various startup backgrounds at the RTP, will share their experience on the process of establishing and running a biotechnology start-up as described above. This session will provide a comprehensive picture that would motivate young scientists to view biological entrepreneurship as an essential future skill.
| 3:30 | Introduction (A. R. Wenck and H. Nguyen) | |
| 3:35 | P-31 | Underground Signaling Networks Philip Benfey, Duke University |
| 3:55 | P-32 | How to Build a Business While You are Deciding on the Perfect Product or Technology to Commercialize? David Reed, Mimetics |
| 4:15 | P-33 | Start Up for Commercialization, Idea Development, and IP Capture: How to Obtain Venture Capital Jeffrey L. Rosichan, AgTech Accelerator |
| 4:35 | P-34 | Intellectual Property Protection for Early Stage Companies Alice M. Bonnen, Myers Bigel, P. A. |
| 4:55 | Discussion |
SECONDARY METABOLITES
Moderator: Jeffrey W. Adelberg, Clemson University
| 3:30 pm – 4:10 pm | Plant Contributed Paper Session | Room 305 |
| 3:30 | P-1015 | A Novel Approach to Cell Selection from Taxus Plant Cell Culture Via an Engineered Mammalian Caspase. Michelle Mckee, Worchester Polytechnic Institute, Maureen Hill, Jeanne Hardy, and Susan Roberts |
| 3:50 | P-1016 | In Vitro Anther Cultures of Camellia assamica ssp. assamica (Masters) for Haploid Plant Production and Possibilities of Accumulation of Catechins, Caffeine and Theophylline in Them Rakhi Chaturvedi, Indian Institute of Technology Guwahati, Vijay Kumar Mishra, and Ruchira Bajpai |
| 5:00 pm – 5:30 pm | SIVB Business Meeting (All Members Are Urged to Attend) Student Award Presentations |
Room 306BC |
| 5:45 pm – 9:00 pm | A Night at the Museum Admittance by Advance Ticket Holders Only |
Off Property |